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48ALTERNATIVETHERAPIESjulaug2011VOL.17NO.4MenopauseTraditionalChineseMedicinevsHormoneTherapyHodaAziziMDPhDx0isx0anx0assistantx0professorx0inx0thex0Schoolx0ofx0Traditionalx0andx0Complementaryx0Medicinex0Mashhadx0Universityx0ofx0Medicalx0Sciencesx0Iranx0andx0wasx0ax0doctoralx0studentx0inx0Dongzhimenx0Hospitalx0afliatedx0withx0Beijingx0Universityx0ofx0Chinesex0Medicinex0China.x0YanFengLiuPhDx0isx0ax0professorx0LinDuMScx0isx0anx0associatex0professorx0andx0XiaoOuXueMDPhDx0isx0ax0professorx0inx0Dongzhimenx0Hospital.x0ChaoHuaWangMScx0isx0ax0professorx0atx0Pekingx0Universityx0Peoplex0Hospitalx0Beijing.x0HamidrezaBahrami-TaghanakiMDMPHPhDx0isx0anx0assistantx0professorx0inx0thex0Schoolx0ofx0Traditionalx0andx0Complementaryx0Medicinex0Mashhadx0Universityx0ofx0Medicalx0Sciencesx0andx0wasx0ax0doctoralx0studentx0inx0Dongzhimenx0Hospital.x0HamidehAziziMDx0wasx0ax0medicalx0stu-dentx0inx0thex0facultyx0ofx0medicinex0Islamicx0Azadx0Universityx0ofx0Mashhadx0Iran.x0HabibOllahEsmailyPhDx0isx0anx0associatex0profes-sorx0ofx0Biostatisticsx0inx0thex0Centerx0forx0Healthx0Sciencesx0Researchx0Schoolx0ofx0Healthx0Mashhadx0Universityx0ofx0Medicalx0Sciences.Correspondingx0authorx0Hodax0Azizix0MDx0PhDx0E-mailx0addressesx0azizihmums.ac.irx0azizi.h.mdgmail.comMenopauseisdeDnedasthepermanentcessationofmenstrualperiodsthatoccursnaturallyorthatisinducedbysurgerychemotherapyorradiation.1Manywomengothroughthemeno-pausaltransitionandpostmenopausewithfewornosymptomswhereasotherspresentsignificantorevendis-ablingsymptomsincludingvasomotorsymptomsVMSsleepdis-turbancesvulvovaginalatrophyseualdysfunctionmooddisturbancesdepressionanietyandirritabilityandsomaticsymptomsbac2painfatigueandstifforpainfuljoints.1-3TheestimatesoftheprevalenceofVMSvaryfrom35to50inperimenopauseandfrom30to80inpostmenopausalwomen.1AstudyonwomenfromsevenSoutheastAsiancountriesfoundfewerVMSinAsianwomenthanWesternwomenbuttheprevalencewasneverthelessnotnegligible.4AnotherstudyonChinesewomenlivinginSydneyagedbetween45and65yearsreportedthat34ofthemeperiencedhotEushesand27eperiencednightsweats.5Previousstudiesestimatedthat75ofwomenover50yearsofageeperienceVMS67and60ofperi-andpostmenopausalwomensee2medicalcarefortheirmenopausalsymptoms.8ThesestatisticshighlighttheimmenseDnancialburdenofVMS.TheimpactofVMShasgainedincreasingimportanceasthelifespanofwomenhasincreasedthroughouttheworld.WomencanepecttospendasigniDcantpor-tionoftheirlivesaftermenopausesomaintainingfunctionalabilityandadesirablequalityoflifeaftermenopauseisofutmostimpor-tance.7HotEushesaffectwor246.0socialactivities44.4leisureactivities47.6sleep82.0mood68.6concentration69.0seualactivity40.9totalenergylevel63.3andoverallqualityoflife69.3inwomenwithVMS.9Theconventionaltreatmentforthisconditionishormonether-apyHTandmanywomensee2HTforthetreatmentofmeno-pausalsymptoms.HoweverasigniDcantnumberofwomenrefuseMenopause-relatedx0Symptomsx0Traditionalx0x0Chinesex0Medicinex0vsx0Hormonex0TherapyHodaAziziMDPhDYanFengLiuPhDLinDuMScChaoHuaWangMScHamidrezaBahrami-Taghana2iMDMPHPhDHabibOllahEsmailyPhDHamidehAziziMDxiaoOuxueMDPhDoriginalresearchObjectivex0TocomparethetherapeuticeffectofChineseherbalmedicineCHMacupunctureandhormonetherapyonmeno-pause-relatedsymptomsofperi-andpostmenopausalwomen.Studyx0designx0Fifty-sevenChinesewomencompleted2monthsoftreatmentwitheitherCHM5gtwicedailyn22acupunc-tureplusCHMkunBaoWan5gtwicedailyplussessionsofacupuncturen20orhormonetherapyn15.Mainx0outcomex0measuresx0kuppermanindescorelevelsoffollicle-stimulatinghormoneFSHandestradiolandthenum-berofsymptomsbeforeandaftertreatmentwerethemainout-comemeasures.Resultsx0CHMacupunctureplusCHMandhormonethera-pysigniDcantlydecreasedkuppermanscorePx0.001ineachgroupandnumberofsymptomsPx0.05.Themeandiffer-enceinkuppermanscorebetweenbaselineand2monthsamongthethreegroupswassigniDcantlyvariedPx0.02.ThedifferencewasonlybetweenacupunctureplusCHMandCHMwithsigniDcantlybetterresultsbyacupunctureplusCHM.AcupunctureplusCHMaswellashormonetherapysigniDcantlyreducedthelevelofFSHPx0.05butCHMalonedidnx19tcauseanysigniDcantdecreaseinFSHlevelsPx0.05.ThemeandifferenceinthelevelofFSHbetweenbaselineand2monthsamongthethreegroupswassigniDcantlydifferentPx0.02.ThisdifferencewasonlybetweenCHMandhor-monetherapywithsigniDcantlybetterresultsbyhormonetherapy.Thethreetreatmentsdidnx19tma2eanysigniDcantincreaseinthelevelofE2Px0.05.Conclusionx0ApplicationofthecombinationofChineseherbalmedicineandacupunctureprovedaseffectiveashormonetherapyinthetreatmentofmenopause-relatedsymptomsanditachievedbetteroutcomesthanherbalmedicinealone.Alternx0Therx0Healthx0Med.201117448-53.